Recombinant adeno-associated virus (rAAV) vectors stand out as highly promising for in vivo gene transfer, particularly in targeting the skeletal muscle for treating muscular genetic diseases or secreting therapeutic factors.Despite the simplicity and efficacy of the established intramuscular (IM) route, it has been often associated with an Beauty
In this work, two tendon tension loading distributions (fixed and moving) are designed to prevent undesired slack and excessive loading in tendons of continuum manipulators.For any given beam configuration, the algorithms utilize the proposed loading distributions to find a new beam configuration Gin Glasses as well as base displacement to control
Water management is challenged by hydrological and socio-economic change and hence often forced to make costly and enduring decisions under uncertainty.Thus, thinking beyond current acknowledged and known limits is important to consider these changes and the dynamic of socio-hydrological interactions.For example, reservoir management aiming at floo
Anne-Catherine Maynard-Paquette,1 Claude Poirier,2 Carl Chartrand-Lefebvre,3,4 Bruno-Pierre Dubé2,5 1Centre Hospitalier de l’Université de Montréal (CHUM), Montreal, Quebec, Canada; 2Centre Hospitalier de l’Université de Montréal (CHUM), Department of Medicine, Respiratory Medicine Division, Montreal,
Sex allocation theory and empirical evidence both suggest that natural selection should favour maternal control of offspring sex ratio in relation to their ability to invest in the offspring.Generalist parasites constitute a particularly interesting group to test this theory as different females commonly utilize different host species showing large